Hi Spence .  Permanent Enamelled Iron Company ,  Aston ,  Birmingham .  It's 1890's era. 

 Just an update, got a full refund and the seller admitted he should have not used the word original. Thanks for all your inputs just took a gamble as had never seen this example with a makers name, should have researched deeper as the Nathaneil and Co address was the wrong area of London. 

 Hello Graham,

Thank you for your inquiry. The short answer is yes! I’ve attached an image of a Bovril advertising campaign from c.1900 that contains the same advertising slogan as your tin plate sign.

 I’ve also attached our Bovril fact sheet for your information.